AFC Summer 2002
July 2002
Scientific Programme
Session 1
Mycobacteria versus Burkholderia
Eshwar Mahenthiralingam. University of Cardiff
The ESAT-6/WXG100 superfamily–and a new mycobacterial secretion system?
Mark J. Pallen
Expression of Toll-like receptors in the lungs of patients with pulmonary tuberculosis
Pauline T. Lukey*, Gael Fenhalls#, Ginette R. Webb*, Liesel Stevens-Muller#, Juanita Bezuidenhout#, Gillian Amphlett* and Ken Duncan*, *GlaxoSmithKline, Stevenage, UK and #University of Stellenbosch, Cape Town, South Africa
Session 2
Heterologous prime-boost immunisation strategies using plasmid DNA and BCG vaccination against tuberculosis
Ferraz J. C. Jr., Colston M. J., Espitia C., Yang M., Coade S., Raynaud C., Lowrie D. B., and Tascon R. E
Characterisation of a Mycobacterium tuberculosis H37Rv transposon library reveals insertions in 351 open reading frames and mutants with altered virulence
Ruth A. McAdam*, Selwyn Quan*, Debbie A. Smith#, Stoyan Bardarov+, Joanna C. Betts*, Fiona C. Cook*, Elizabeth U. Hooker*, Alan Lewis*, Peter Woollard*,Martin J. Everett*, Pauline T. Lukey*, Gregory J. Bancroft#, William R. Jacobs Jr+, and Ken Duncan*; *GlaxoSmithKline, #London School Of Hygiene & Tropical Medicine and +Albert Einstein College of Medicine
From CTL to TRL to MRU: The history of the reference laboratory
Tony Jenkins
Session 3
Are the Rpf family of growth factors essential for bacterial multiplication?
G V Mukamolova, O A Turapov, D I Young, C L Finan, A S Kaprelyants, D B Kell & M Young
Hsp65 DNA Vaccination in a mouse aerosol challenge system
B Walker, A Thiobhani, M Addawe, NIBSC
Phospho-threonine-binding FHA domains in mycobacterial proteins–neglected players in the phospho-signalling game?
Mark J. Pallen, Arshad M. Khan, Roy Chaudhuri
Session 4
Modification of nat, the gene encoding arylamine N-acetyltransferase which acetylates isoniazid, affects the growth and cellular morphology of mycobacteria
Sanjib Bhakta, Anna Upton, Frederique Pompeo, Mark Payton, Edith Sim, Tanya Parish
Operomics – towards an operon map of M. tuberculosis
Neil Stoker
Rapid Genomic and Biological Characterisation Of The Leicester School Tuberculosis Outbreak Strain
Jamila Shafi. Department of Microbiology and Immunology, University of Leicester, UK