AFC Winter 2009

Held at the NIMR, Mill Hill

January 9th 2009

Scientific Programme

Session 1

Identification of small RNAs in Mycobacterium tuberculosis
Kristine B. Arnvig and Douglas B. Young. NIMR, London

Identification of TB contacts with latent TB infection in a population with a high HIV and TB burden
Kerry A Millington,Junior Mutsvangwa, Kathryn Chaka, Tafadzwa Mavhudzi, Yin-Bun Cheung, Peter R Mason, , Anthony E Butterworth, Elizabeth L Corbett and Ajit Lalvani. Imperial College, London

Characterisation of a putative dihydrofolate reductase from Mycobacterium smegmatis
Dimitrios Evangelopoulos, Nathan Lack, Giles Robertson, Tina Daviter, Nicholas H. Keep, Edith Simand Sanjib Bhakta. Birkbeck College, University of London

Changes in T cell population dynamics in 3 species: Dynamics of white cell populations in M. tuberculosis infection in rhesus macaques
K Gooch, S Sharpe, A Williams, M Dennis, P D Marsh. Health Protection Agency, CEPR, Porton Down

Detection and molecular characterization of 9000-year old Mycobacterium tuberculosis from a Neolithic settlement in the Eastern Mediterranean
Oona Lee, David Minnikin, Gurdyal Besra, Israel Hershkovitz, Vered Eshed, Ehud Galili, Charles Greenblatt, Eshetu Lemma, Gila Kahila Bar-Gal, Mark Spigelman, Helen Donoghue. University of Birmingham

Session 2

Inhibition of phago-lysosome fusion by Mycobacterium bovis BCG induces a Niemann-Pick type C1-like phenotype
Emyr Lloyd-Evans, Nathan Lack, Edith Sim and Frances M. Platt. University of Oxford

KstR2: Identification of a second TetR-type regulator involved in cholesterol catabolism in mycobacteria
Sharon Kendall, Annemieke ten Bokum, Phillipa Burgess, Mike Withers, Iria Uhia Castro, Nwaamaka Owoh, Nadia Mokhtar and Neil Stoker. The Royal Veterinary College, London

Intranasal vaccination with an ESAT-6 expressing attenuated influenza vaccine
A. Egorov. AVIR Green Hills Biotechnology, Vienna

BCG vaccination induces polyfunctional CD4+ T cells in the spleen which correlate with active immunity to a Mycobacterium bovis challenge
Philip J Hogarth. Veterinary Laboratories Agency, Weybridge.

The Burden of Mycobacterial Disease in Ethiopian Cattle
Stefan Berg, Rebuma Firdessa, Endalamaw Gadisa, Meseret Habtamu, Araya Mengistu, Lawrence Yamuah, Gobena Ameni, Brian D. Robertson, Douglas B. Young, Howard Engers, Noel H. Smith, Martin Vordermeier, R. Glyn Hewinson, Abraham Aseffa, and Stephen V. Gordon. Veterinary Laboratories Agency, Weybridge