AFC Winter 2011 meeting

AFC Winter 2011

Held at St George’s University of London

January 7th 2011

Scientific Programme

Session 1

Tandem duplications of large genomic islands in Mycobacterium avium subspecies paratuberculosis associated with human strains isolated from patients with Crohn’s disease
Tim Bull, Richard Linedale, Wojtek Michalski, James Wynne. Department of Cellular and Molecular Medicine, Division of Clinical Sciences, St George’s, University of London

Functional analysis of the serine-threonine protein kinase, PknF, and its substrate the ABC transporter Rv1747, in Mycobacterium tuberculosis
Vicky L. Spivey, Virginie Molle, Rachael H. Whalan, Angela Rodgers, Apoorva Bhatt, Lasse Stach, Elizabeth M. Hirst, Gurdyal S. Besra, K. Barry Walker, Stephen J. Smerdon, Roger S. Buxton. MRC National Institute for Medical Research

Identification of biomarkers of treatment response in blood by transcriptomic analysis
Jackie Cliff, Ji-Sook Lee, Nicholas Constantinou, Jang-Eun Cho, Taane Clark, Katharina Ronacher, Paul van Helden, Gerhard Walzl, Hazel Dockrell. Department of Immunology and Infection, London School of Hygiene & Tropical Medicine

Gene products HsaD and HsaC in cholesterol metabolism of Mycobacterium tuberculosis
M. Abdul Aziz, N. Lack, R. Ballet, V. Cheng, N. Laurieri, S. Keany, A. Ryan, & E. Sim. Department of Pharmacology, University of Oxford

Lung heparin targeted vaccine delivery of mycobacterial antigens
Elena Stylianou, Ilaria Pepponi, Craig van Dolleweerd, Julian Ma and Rajko Reljic Division of Clinical Sciences, St George’s, University of London

Session 2

Immunological responses following BCG vaccination and Mycobacterium bovis challenge in the Eurasian badger
Roland Ashford, Sandrine Lesellier, Si Palmer, Sonya Gowtage, Deanna Dalley, Dipesh Dave, Laura Chamberlain, Benjamin Grundy, R.Glyn Hewinson, Brian Catchpole, Frank E. Aldwell, and Mark Chambers. Veterinary Laboratories Agency

Mycobacterium tuberculosis acg in the hspX gene cassette is required for growth and virulence in vivo
Yanmin Hu and Anthony R. M. Coates. Centre of Infection and Immunity, Division of Clinical Sciences, St George’s University of London

Identification of novel non-tuberculous mycobacterial antigens
A Checkley, D Wyllie, I Satti, T Scriba, H Fletcher, A Hill, W Hanekom, H McShane. Jenner Vaccine Institute, Oxford University

Analysis of M. tuberculosis strains from the North London isoniazid resistant outbreak shows independent evolution of drug resistance
R.J. Shorten, A. McGregor, S.H. Gillespie, C. Jenkins, S. Platt and T.D. McHugh. Department of Medical Microbiology, Royal Free Hospital, London & Centre for Clinical Microbiology, University College London

Differential small RNA expression across Mycobacterium bovis field strains
P. Golby, J. Nunez, J. Hinds, A. Witney, S. Bentley, G. Hewinson and S. Gordon. Veterinary Laboratories Agency